Article
Nitric oxide is necessary for a switch from stationary to locomoting phenotype in epithelial cells.
The American journal of physiology - 1 Mar 1996
Noiri E, Peresleni T, Srivastava N, Weber P, Bahou W F, Peunova N, Goligorsky M S
Abstract excerpt
The restitution of epithelial integrity is accomplished in part by cell migration. Studying this process, we have found that nitric oxide (NO) release migrating epithelial BSC-1 cells displayed a biphasic response to the inflicted wounds; an initial transient release of NO is followed by a delayed sustained elevation. Whereas the constitutive endothelial NO synthase (NOS) did not show any spatial or temporal...
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