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Article

Folding and unfolding kinetics of the proline-to-alanine mutants of bovine pancreatic ribonuclease A.

Biochemistry - 6 Feb 1996

Dodge R W, Scheraga H A

Abstract excerpt

Four single mutants (P42A, P93A, P114A, and P117A) of bovine pancreatic ribonuclease A (RNase A) in which each mutant has one of the four prolines of RNase A changed to alanine were prepared. The physical properties of these four mutants indicate that their native structure is essentially identic...

Topics

Alanine
Animals
Cattle
Genes, Synthetic
Guanidine
Guanidines
Isomerism
Kinetics
Models, Chemical
Mutation
Pancreas
Proline
Protein Denaturation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Folding

Recombinant Proteins

Ribonuclease, Pancreatic

Source

Identifiers

PMID: 8634286
DOI: 10.1021/bi952348q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8634286-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Folding and unfolding kinetics of the proline-to-alanine mutants of bovine pancreatic ribonuclease A.PMID 8634286Read ↗

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