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Article

A Large Variety of Alternatively Spliced and Differentially Expressed mRNAs Are Encoded by the Human Acute Myeloid Leukemia Gene AML1

1 Mar 1996

Abstract excerpt

The human chromosome 21 acute myeloid leukemia gene AML1 is frequently rearranged in the leukemia-associated translocations t(8;21) and t(3;21), generating fused proteins containing the amino-terminal part of AML1. In normal blood cells, five size classes (2-8 kb) of AML1 mRNAs have been previously observed. We isolated seven cDNAs corresponding to various AML1 mRNAs. Sequencing revealed that their size...

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Identifiers

PMID: 8634147
DOI: 10.1089/dna.1996.15.175

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A Large Variety of Alternatively Spliced and Differentially Expressed mRNAs Are Encoded by the Human Acute Myeloid Leukemia Gene AML1PMID 8634147Read ↗

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