Article
Rapid and simple approach for identification of Mycobacterium tuberculosis complex isolates by PCR-based genomic deletion analysis.
Journal of clinical microbiology - 1 Jul 2002
Parsons Linda M, Brosch Roland, Cole Stewart T, Somoskövi Akos, Loder Arthur, Bretzel Gisela, Van Soolingen Dick, Hale Yvonne M, Salfinger Max
Abstract excerpt
Although the virulences and host ranges differ among members of the Mycobacterium tuberculosis complex (TBC; M. tuberculosis, M. africanum, M. canettii, M. microti, M. bovis, and M. bovis BCG), commercially available molecular assays cannot differentiate these organisms because of the genetic identities of their 16S rRNA gene sequences. Comparative genomic analyses with the complete DNA sequence of M....
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