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Liver disease in adults with α1‐antitrypsin deficiency

1 Mar 2018

Abstract excerpt

BACKGROUND: The natural history of adult liver disease due to α1-antitrypsin deficiency (A1AD) remains poorly understood. OBJECTIVE: We investigated whether heterozygosity for the Z-allele predisposes for the development of clinically significant portal hypertension (CSPH). Moreover, we aimed to non-invasively assess the prevalence of liver fibrosis and hepatic steatosis in adults with A1AD treated by...

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PMID: 30083333
DOI: 10.1177/2050640618764057

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