The additive to background assumption in cancer risk assessment: A reappraisal.

doi:10.1016/j.envres.2018.05.015

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Article

The additive to background assumption in cancer risk assessment: A reappraisal.

Environmental research - 1 Oct 2018

Calabrese Edward J

Abstract excerpt

The assumption that chemical and radiation induced cancers act in a manner that is additive to background was proposed in the mid-1970s. It was adopted by the U.S. Environmental Protection Agency (EPA) in 1986 and then subsequently by other regulatory agencies worldwide for cancer risk assessment. It ensured that cancer risks at low doses act in a linear fashion. The additive to background process assumes that...

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PMID: 29890424
DOI: 10.1016/j.envres.2018.05.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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