Article
Radiation risk is linear with dose at low doses.
The British journal of radiology - 1 Jan 2005
Chadwick K H, Leenhouts H P
Abstract excerpt
This paper presents a brief argument, based on a mechanistic approach, to show that radiation risk is linear with radiation dose from zero dose up. Similarities in cellular effects lead to the assumption of a common mechanism and the DNA double strand break is identified as the crucial radiation-induced lesion. A cancer model extends the cellular effects to the main radiation risk providing confirmation of the...
Topics
- DNA
- DNA Damage
- Dose-Response Relationship, Radiation
- Humans
- Mutation
- Neoplasms
- Radiation Dosage
- Radiation Injuries
- Risk Factors