Molecular scanning of the insulin receptor gene in women with polycystic ovarian syndrome.

doi:10.1210/jcem.81.5.8626868

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Article

Molecular scanning of the insulin receptor gene in women with polycystic ovarian syndrome.

The Journal of clinical endocrinology and metabolism - 1 May 1996

Talbot J A, Bicknell E J, Rajkhowa M, Krook A, O'Rahilly S, Clayton R N

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a common disorder characterized by chronic anovulation and infertility, hyperandrogenaemia, and frequently insulin resistance. This study investigated whether mutations in the insulin receptor gene could explain the insulin resistance in subjects with PCOS. Fro...

Topics

Blotting, Southern
DNA
Exons
Female
Humans
Insulin Resistance
Mutation
Polycystic Ovary Syndrome
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Receptor, Insulin

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