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Article

Absence of insulin receptor gene mutations in three insulin-resistant women with the polycystic ovary syndrome.

Metabolism: clinical and experimental - 1 Dec 1994

Sorbara L R, Tang Z, Cama A, Xia J, Schenker E, Kohanski R A, Poretsky L, Koller E, Taylor S I, Dunaif A

Abstract excerpt

Women with polycystic ovary syndrome (PCOS) are markedly insulin-resistant, but the molecular mechanisms of these changes and their relationship to the hyperandrogenic state remain to be clarified. Mutations have recently been identified in the insulin receptor gene of patients with extreme forms of insulin resistance associated with hyperandrogenism (eg, type A insulin resistance), and these mutations account...

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PMID: 7990713
DOI: 10.1016/0026-0495(94)90018-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Absence of insulin receptor gene mutations in three insulin-resistant women with the polycystic ovary syndrome.PMID 7990713Read ↗

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