Article
The mec-8 gene of C. elegans encodes a protein with two RNA recognition motifs and regulates alternative splicing of unc-52 transcripts.
Development (Cambridge, England) - 1 May 1996
Lundquist E A, Herman R K, Rogalski T M, Mullen G P, Moerman D G, Shaw J E
Abstract excerpt
Mutations in the mec-8 gene of Caenorhabditis elegans were previously shown to affect the functions of body wall muscle and mechanosensory and chemosensory neurons. Mutations in mec-8 also strongly enhance the mutant phenotype of specific mutations in unc-52, a gene that encodes, via alternative...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cloning, Molecular
- Gene Expression Regulation
- Genes, Helminth
- Helminth Proteins
- Membrane Proteins
- Models, Genetic
- Molecular Sequence Data
- Mutation
- Phenotype
- Proteoglycans
- RNA, Helminth