Article
Renal cell carcinoma of end-stage renal disease: a histopathologic and molecular genetic study.
Journal of the American Society of Nephrology : JASN - 1 Nov 1996
Hughson M D, Schmidt L, Zbar B, Daugherty S, Meloni A M, Silva F G, Sandberg A A
Abstract excerpt
Renal cell carcinomas (RCC) are responsible for the deaths of 3% to 4% of patients with ESRD. The clear cell carcinoma of the kidney, which comprises 80% of sporadic RCC within the general population, shows a deletion of gene sequences in the short arm of chromosome 3 (3p) in as many as 100% of c...
Topics
- Adult
- Aged
- Carcinoma, Renal Cell
- DNA Probes
- DNA, Neoplasm
- Female
- Gene Deletion
- Humans
- Kidney Failure, Chronic
- Kidney Neoplasms
- Ligases
- Male
- Middle Aged
- Mutation
- Polymorphism, Single-Stranded Conformational
- Proteins
- Retrospective Studies
- Tumor Suppressor Proteins