Article
Incidence of the Nak(a)-negative platelet phenotype in African Americans is similar to that of Asians.
Transfusion - 1 Apr 1996
Curtis B R, Aster R H
Abstract excerpt
BACKGROUND: About 5 to 10 percent of Asians have platelets that lack the major membrane glycoprotein (GP) IV (CD36, GPIIIb) that carries the isoantigen Naka. The GPIV-negative platelet phenotype is extremely rare among whites, but its frequency in persons of African ancestry has not yet been determined. Isoimmunization against GPIV can occur in GPIV-negative persons and can lead to platelet transfusion...
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