Article
Typing for human platelet alloantigens.
Reviews in immunogenetics - 1 Jan 1999
Juji T, Saji H, Satake M, Tokunaga K
Abstract excerpt
Antibodies to platelet alloantigens, and sometimes to isoantigens, induce severe clinical problems such as neonatal alloimmune thrombocytopenia (NAIT), post-transfusion purpura (PTP) and refractoriness to platelet transfusions (PTR). For example, NAIT affects approximately 1 in 5,000 live births. It is essential, therefore, to screen pregnant women for platelet antibodies in order to save babies' lives. Almost 40...
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