Human platelet antigens - 2013.

doi:10.1111/vox.12085

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Article

Human platelet antigens - 2013.

Vox sanguinis - 1 Feb 2014

Curtis B R, McFarland J G

Abstract excerpt

To date, 33 human platelet alloantigens (HPAs) have been identified on six functionally important platelet glycoprotein (GP) complexes and have been implicated in alloimmune platelet disorders including foetal and neonatal alloimmune thrombocytopenia (FNAIT), posttransfusion purpura (PTP) and multitransfusion platelet refractoriness (MPR). The greatest number of recognized HPA (20 of 33) resides on the GPIIb/IIIa...

Topics

Alleles
Antigens, Human Platelet
Genotyping Techniques
Humans
Platelet Glycoprotein GPIIb-IIIa Complex
Platelet Membrane Glycoproteins
Polymorphism, Single Nucleotide

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Open in PubMed

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PMID: 24102564
DOI: 10.1111/vox.12085

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