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Article

Platelet CD36 deficiency is present in 2.6% of Arabian individuals and can cause NAIT and platelet refractoriness.

Transfusion - 1 Jun 2021

Flesch Brigitte K, Scherer Vanessa, Opitz Andreas, Ochmann Oswin, Janson Anne, Steitz Monika, Zeiler Thomas

Abstract excerpt

BACKGROUND: CD36 isoantibodies are capable of inducing neonatal alloimmune thrombocytopenia (NAIT) and platelet refractoriness. As to now the CD36 type I deficiency has been reported in East Asian and African individuals. However, it is virtually unknown in Caucasians. The aim of this study was to display the prevalence of the CD36 deficiency within parts of the Arabian population in Germany. Secondly, we are...

Topics

Blood Platelets
CD36 Antigens
Female
Gene Deletion
Gene Expression
Germany
Humans
Infant, Newborn
Male
Mutation
Pedigree
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Thrombocytopenia, Neonatal Alloimmune

Source

Identifiers

PMID: 33822386
DOI: 10.1111/trf.16398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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