Article
Clinical evidence for genomic imprinting in bipolar I disorder.
Acta psychiatrica Scandinavica - 1 Nov 1995
Grigoroiu-Serbanescu M, Nothen M, Propping P, Poustka F, Magureanu S, Vasilescu R, Marinescu E, Ardelean V
Abstract excerpt
The phenotypic indicators of the genomic imprinting model were applied to clinical psychopathology data on 100 bipolar (BP) I probands and their families. The paternal transmission was associated with a significantly younger age of onset of the BP illness in probands and a higher rate of affective disorders in first- and second-degree relatives. The effect of the sex of the transmitting parent on age of onset in...
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