Relevance of early age-of-onset in genetic studies of bipolar affective disorder.

doi:10.1097/00004583-199207000-00005

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Article

Relevance of early age-of-onset in genetic studies of bipolar affective disorder.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Jul 1992

Strober M

Abstract excerpt

Early age-of-onset appears to predict higher familial loading in bipolar affective disorder. This finding, coupled with ongoing attention to the importance of genomic heterogeneity for segregation and linkage analyses, underscores the value of research on juvenile samples. This research is review...

Topics

Bipolar Disorder
Child
Chromosome Mapping
Genetic Linkage
Humans
Phenotype
Risk Factors

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