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Article

Evidence for cell-specific regulation of transcription of the rat alpha2A-adrenergic receptor gene.

Hypertension (Dallas, Tex. : 1979) - 1 Apr 1996

Handy D E, Gavras H

Abstract excerpt

We investigated the transcriptional activity of the -131 to -92 region of the rat alpha2A-adrenergic receptor gene. In HT29 cells, this region has a positive effect on transcription, whereas in RINm5F cells, this region has a negative effect on transcription. The -131 to -92 region has a GC box (GGGGCGG) surrounded by overlapping GGAGG repeats. To analyze nuclear factor binding to this region, we made a series of...

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PMID: 8613257
DOI: 10.1161/01.hyp.27.4.1018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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