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Article

Effect of a regulatory mutation on the rat atrial natriuretic peptide gene transcription.

Peptides - 1 Mar 2002

Rubattu Speranza, Giliberti Rosangela, De Paolis Paola, Stanzione Rosita, Spinsanti Paola, Venturelli Vanessa, Volpe Massimo

Abstract excerpt

To investigate the functional relevance of a regulatory mutation affecting the enhancer element PEA2 of the rat ANP gene we transfected rat cardiomyocytes and aortic endothelial cells with either the mutant or the wild-type ANP promoter construct (-683 +54) and performed CAT assays both at baseline and in response to Phenylephrine and Angiotensin II. In the myocardial cells we also determined the DNA/nuclear...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11836006
DOI: 10.1016/s0196-9781(01)00626-x

Genes

CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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