Article
Genetic characterization of the "new" Harlan Sprague Dawley Dahl salt-sensitive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 1996
Walder R Y, Morgan D A, Haynes W G, Sigmund R D, McClain A M, Stokes J B, Mark A L
Abstract excerpt
In 1994, it was reported that Dahl salt-sensitive SS/Jr rats supplied by Harlan Sprague Dawley were genetically contaminated and resistant to the pressor effects of a high salt diet. Harlan Sprague Dawley subsequently developed new pedigree expansion and production colonies from their foundation colony to supply new, purportedly inbred, Harlan Sprague Dawley SS/Jr (S(HSD)). To evaluate the genetic integrity and...
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