Article
Genetic characterization of the "new" Harlan Sprague Dawley Dahl salt-sensitive rats.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 1996
Walder R Y, Morgan D A, Haynes W G, Sigmund R D, McClain A M, Stokes J B, Mark A L
Abstract excerpt
In 1994, it was reported that Dahl salt-sensitive SS/Jr rats supplied by Harlan Sprague Dawley were genetically contaminated and resistant to the pressor effects of a high salt diet. Harlan Sprague Dawley subsequently developed new pedigree expansion and production colonies from their foundation...
Topics
- Animals
- Blood Pressure
- Female
- Genotype
- Male
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Sodium, Dietary