Mutants lacking myosin II cannot resist forces generated during multicellular morphogenesis.

doi:10.1242/jcs.108.3.1105

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Article

Mutants lacking myosin II cannot resist forces generated during multicellular morphogenesis.

Journal of cell science - 1 Mar 1995

Shelden E, Knecht D A

Abstract excerpt

We have used fluorescent labeling, confocal microscopy and computer-assisted motion analysis to observe and quantify individual wild-type and myosin II mutant cell behavior during early multicellular development in Dictyostelium discoideum. When cultured with an excess of unlabeled wild-type cell...

Topics

Animals
Cell Movement
Cell Size
Cyclic AMP
Dictyostelium
Gene Deletion
Microscopy, Confocal
Microscopy, Fluorescence
Myosins
Phenotype
Signal Transduction

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