Article
Mutants lacking myosin II cannot resist forces generated during multicellular morphogenesis.
Journal of cell science - 1 Mar 1995
Shelden E, Knecht D A
Abstract excerpt
We have used fluorescent labeling, confocal microscopy and computer-assisted motion analysis to observe and quantify individual wild-type and myosin II mutant cell behavior during early multicellular development in Dictyostelium discoideum. When cultured with an excess of unlabeled wild-type cells, labeled control cells are randomly distributed within aggregation streams, while myosin II mutant cells are found...
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