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Article

Human beta2-glycoprotein I as an anticardiolipin cofactor determined using mutants expressed by a baculovirus system

15 Apr 1996

Abstract excerpt

beta2-Glycoprotein I (beta2-GPI) consists of five repeats of a homologous domain. We designed a series of human beta2-GPI mutant genes, ie, three mutant genes lacking the domain(s) present in the NH2-terminal region and two of those present in the COOH-terminal region. These mutant genes were expressed in Spodoptera frugiperda insect cells (Sf9) infected with recombinant baculoviruses and the mutant proteins were...

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Identifiers

PMID: 8605342
DOI: 10.1182/blood.v87.8.3262.bloodjournal8783262

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