Article
Genetic linkage of Wagner disease and erosive vitreoretinopathy to chromosome 5q13-14.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 May 1995
Brown D M, Graemiger R A, Hergersberg M, Schinzel A, Messmer E P, Niemeyer G, Schneeberger S A, Streb L M, Taylor C M, Kimura A E
Abstract excerpt
BACKGROUND: Wagner disease and erosive vitreoretinopathy are potentially blinding autosomal dominant diseases that share some similarities with Stickler syndrome. However, both disorders have associated retinal pigment epithelial changes, poor night vision, visual field defects, and abnormal electroretinographic findings, which are not found in families with COL2A1-associated Stickler syndrome. In addition,...
Topics
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 5
- DNA
- DNA Primers
- Fundus Oculi
- Genetic Linkage
- Genotype
- Granulomatosis with Polyangiitis
- Humans
- Lod Score