Article
Immunolocalization of beta ig-h3 protein in 5q31-linked corneal dystrophies and normal corneas.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 1999
Streeten B W, Qi Y, Klintworth G K, Eagle R C, Strauss J A, Bennett K
Abstract excerpt
OBJECTIVE: To characterize the relation of the beta ig-h3 protein to the diagnostic corneal deposits in the hereditary corneal dystrophies recently shown to have mutations in the beta ig-h3 gene on chromosome 5q31. METHODS: Corneas with lattice, granular, mixed granular-lattice ("Avellino"), and...
Topics
- Adult
- Aged
- Chromosomes, Human, Pair 5
- Cornea
- Corneal Dystrophies, Hereditary
- Extracellular Matrix Proteins
- Genetic Linkage
- Humans
- Immunoenzyme Techniques
- Microscopy, Immunoelectron
- Middle Aged
- Mutation
- Neoplasm Proteins
- Transforming Growth Factor beta