Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editing.

Cell - 22 Mar 1996

Seiwert S D, Heidmann S, Stuart K

Abstract excerpt

Deletion of uridylates from the 3'-most editing site of synthetic ATPase 6 pre-mRNA can be visualized directly by coincubation of a radiolabeled substrate RNA and a synthetic gRNA in 20S fractions of T.brucie mitochondrial lysates. Substrate RNA cleavage is gRNA directed and occurs 3' to the uridylates to be deleted. U residues appear to be sequentially removed from the 3' end of the 5' cleavage product prior to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphatases
Share to Base Sequence
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Nucleic Acid Conformation

Share to RNA Precursors

Share to Substrate Specificity

Share to Time Factors

Source

Identifiers

PMID: 8601307
DOI: 10.1016/s0092-8674(00)81062-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editing.PMID 8601307Read ↗

RNA editing in kinetoplastid protozoaSemantic proximity Read ↗

RNA editing in kinetoplastidsSemantic proximity Read ↗

A mRNA determinant of gRNA-directed kinetoplastid editing.Semantic proximity Read ↗

‘Gestalt,’ Composition and Function of the <i>Trypanosoma brucei</i> EditosomeSemantic proximity Read ↗

Native mitochondrial RNA-binding complexes in kinetoplastid RNA editing differ in guide RNA compositionSemantic proximity Read ↗

In vivo cleavage specificity of Trypanosoma brucei editosome endonucleasesSemantic proximity Read ↗

Isolation of RNA binding proteins involved in insertion/deletion editing.Semantic proximity Read ↗

RNA editing in kinetoplastid protozoa.Semantic proximity Read ↗

Dyskinetoplastic Trypanosoma brucei contains functional editing complexes.Semantic proximity Read ↗

Uridine insertion/deletion RNA editing in trypanosome mitochondria: A complex businessSemantic proximity Read ↗

Trypanosoma brucei RNA Editing: Coupled Cycles of U Deletion Reveal Processive Activity of the Editing ComplexSemantic proximity Read ↗

RNA editing: transfer of genetic information from gRNA to precursor mRNA in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.