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Article

Viral resistance and the selection of antiretroviral combinations.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 1 Jan 1995

Larder B A

Abstract excerpt

Mounting scientific evidence suggests that viral replication and evolution of diversification, with the resulting emergence of variants including drug-resistant strains, is responsible for the gradual destruction of the immune system and is the mechanism of disease progression in HIV-infected pat...

Topics

Antiviral Agents
Drug Resistance, Microbial
Drug Resistance, Multiple
Drug Therapy, Combination
HIV Infections
HIV Protease Inhibitors
HIV-1
Humans
Mutation
Reverse Transcriptase Inhibitors
Virus Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Zidovudine

Source

Identifiers

PMID: 8595505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8595505-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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