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Article

Use of genetic analyses to probe structure, function, and dynamics of bacteriophage T4 DNA polymerase.

Methods in enzymology - 1 Jan 1995

Reha-Krantz L J

Abstract excerpt

Functionally distinct mutant DNA polymerases have been isolated by the genetic selection strategies described here. These methods can be supplemented by the use of targeted mutagenesis procedures to enhance mutagenesis of DNA polymerase genes and to direct mutagenesis to specific sites in cloned DNA polymerases (see [22-24, 28], this volume). The power of genetic selection is in the ability to identify amino acid...

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PMID: 8594358
DOI: 10.1016/0076-6879(95)62027-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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