Article
Association of the angiotensinogen M235T and angiotensin-converting enzyme insertion/deletion gene polymorphisms in Turkish type 2 diabetic patients with and without nephropathy.
Journal of diabetes and its complications - 1 Jan 2000
Eroglu Zuhal, Cetinkalp S, Erdogan Mehmet, Kosova B, Karadeniz Muammer, Kutukculer A, Gunduz C, Tetik A, Topcuoglu N, Ozgen A G, Tuzun M
Abstract excerpt
OBJECTIVE: Recent studies have suggested an association between a deletion variant of the angiotensin-converting enzyme (ACE) gene and diabetic nephropathy. However, this finding has not been confirmed by all investigators. Furthermore, an M235T variant of the angiotensinogen (AGT) gene has been associated with hypertension, an important risk factor for the development and progression of diabetic nephropathy....
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