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Article

Genetic manipulation of polyphosphate metabolism affects cadmium tolerance in Escherichia coli.

Applied and environmental microbiology - 1 Feb 1996

Keasling J D, Hupf G A

Abstract excerpt

The polyphosphate metabolic pathways in Escherichia coli were genetically manipulated to test the effect of polyphosphate on tolerance to cadmium. A polyphosphate kinase (ppk) and polyphosphatase (ppx) mutant strain produced no polyphosphate, whereas the same strain carrying multiple copies of ppk on a high-copy plasmid produced significant quantities. The doubling times of both strains increased with increasing...

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Identifiers

PMID: 8593078
DOI: 10.1128/aem.62.2.743-746.1996
PMCID: PMC167843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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