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Article

Pyrophosphatase is essential for growth of Escherichia coli.

Journal of bacteriology - 1 Oct 1990

Chen J, Brevet A, Fromant M, Lévêque F, Schmitter J M, Blanquet S, Plateau P

Abstract excerpt

The ppa gene for inorganic pyrophosphatase is essential for the growth of Escherichia coli. A recombinant with a chromosomal ppa::Kanr lesion and a temperature-sensitive replicon with a ppa+ gene showed a temperature-sensitive growth phenotype, and a mutant with the sole ppa+ gene under control of the lac promoter showed inducer-dependent growth. When the lacp-ppa mutant was subcultured without inducer, the...

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Identifiers

PMID: 2170325
DOI: 10.1128/jb.172.10.5686-5689.1990
PMCID: PMC526883

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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