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Article

A method to estimate effects of amino acid substitutions in blood coagulation factor IX from hemophilia B patients.

Medinfo. MEDINFO - 1 Jan 1995

Furutani H

Abstract excerpt

Hemophilia B is a hereditary disease caused by defects in coagulation factor IX. Accumulation of sequence data in the hemophilia B database makes it possible to study this disease at the molecular level. The most common mutations reported in the database are amino acid substitutions. Activity of factor IX in a patient's blood depends on a position of the substitution and combination of original and substituting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 8591581

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PAM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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