Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Drosophila E74 gene is required for metamorphosis and plays a role in the polytene chromosome puffing response to ecdysone.

Development (Cambridge, England) - 1 May 1995

Fletcher J C, Burtis K C, Hogness D S, Thummel C S

Abstract excerpt

The steroid hormone ecdysone initiates Drosophila metamorphosis by reprogramming gene expression during late larval and prepupal development. The ecdysone-inducible gene E74, a member of the ets proto-oncogene family, has been proposed to play a key role in this process. E74 is encoded within the 74EF early puff and consists of two overlapping transcription units, E74A and E74B. To assess the function(s) of E74...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Drosophila

Share to Molecular Sequence Data

Share to Mutation

Share to Phenotype

Share to Transcription Factors

Source

Identifiers

PMID: 7789275
DOI: 10.1242/dev.121.5.1455

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Drosophila E74 gene is required for metamorphosis and plays a role in the polytene chromosome puffing response to ecdysone.PMID 7789275Read ↗

The Drosophila E74 gene is required for the proper stage- and tissue-specific transcription of ecdysone-regulated genes at the onset of metamorphosis.Semantic proximity Read ↗

The 82F late puff contains the L82 gene, an essential member of a novel gene family.Semantic proximity Read ↗

The E23 early gene of Drosophila encodes an ecdysone-inducible ATP-binding cassette transporter capable of repressing ecdysone-mediated gene activation.Semantic proximity Read ↗

The L63 gene is necessary for the ecdysone-induced 63E late puff and encodes CDK proteins required for Drosophila development.Semantic proximity Read ↗

Genetic analysis of the Drosophila 63F early puff. Characterization of mutations in E63-1 and maggie, a putative Tom22.Semantic proximity Read ↗

Broad-Complex, E74, and E75 early genes control DNA puff BhC4-1 expression in prepupal salivary glands.Semantic proximity Read ↗

The ecdysone-inducible Broad-complex and E74 early genes interact to regulate target gene transcription and Drosophila metamorphosis.Semantic proximity Read ↗

Loss of the ecdysteroid-inducible E75A orphan nuclear receptor uncouples molting from metamorphosis in Drosophila.Semantic proximity Read ↗

The DHR78 nuclear receptor is required for ecdysteroid signaling during the onset of Drosophila metamorphosis.Semantic proximity Read ↗

Genetic control of specificity to steroid-triggered responses in Drosophila.Semantic proximity Read ↗

Control of target gene specificity during metamorphosis by the steroid response gene E93.Semantic proximity Read ↗

The Drosophila Broad-Complex plays a key role in controlling ecdysone-regulated gene expression at the onset of metamorphosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.