Article
Evolutionary dynamics of human rotaviruses: balancing reassortment with preferred genome constellations.
PLoS pathogens - 1 Oct 2009
McDonald Sarah M, Matthijnssens Jelle, McAllen John K, Hine Erin, Overton Larry, Wang Shiliang, Lemey Philippe, Zeller Mark, Van Ranst Marc, Spiro David J, Patton John T
Abstract excerpt
Group A human rotaviruses (RVs) are a major cause of severe gastroenteritis in infants and young children. Yet, aside from the genes encoding serotype antigens (VP7; G-type and VP4; P-type), little is known about the genetic make-up of emerging and endemic human RV strains. To gain insight into t...
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