Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular cloning, expression pattern, and chromosomal localization of human CDKN2D/INK4d, an inhibitor of cyclin D-dependent kinases.

Genomics - 10 Oct 1995

Okuda T, Hirai H, Valentine V A, Shurtleff S A, Kidd V J, Lahti J M, Sherr C J, Downing J R

Abstract excerpt

Progression through the G1 phase of the cell cycle is dependent on the activity of holoenzymes formed between D-type cyclins and their catalytic partners, the cyclin-dependent kinases cdk4 and cdk6. p16INK4a, p15INK4b, and p18INK4c, a group of structurally related proteins, function as specific inhibitors of the cyclin D-dependent kinases and are likely to play physiologic roles as specific regulators of these...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carrier Proteins

Share to Cell Cycle

Share to Chromosome Mapping

Share to Cloning, Molecular

Share to DNA Primers

Source

Identifiers

PMID: 8575754
DOI: 10.1006/geno.1995.9957

Genes

PBX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular cloning, expression pattern, and chromosomal localization of human CDKN2D/INK4d, an inhibitor of cyclin D-dependent kinases.PMID 8575754Read ↗

Distinct versus redundant properties among members of the INK4 family of cyclin‐dependent kinase inhibitorsSemantic proximity Read ↗

<i>INK4d</i>-Deficient Mice Are Fertile Despite Testicular AtrophySemantic proximity Read ↗

Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia–lymphoma cellsSemantic proximity Read ↗

Lack of mutation in the cyclin-dependent kinase inhibitor, p19INK4d, in tumor-derived cell lines and primary tumors.Semantic proximity Read ↗

Structure of the cyclin-dependent kinase inhibitor p19Ink4d.Semantic proximity Read ↗

Genomic organization, chromosomal localization, and independent expression of human cyclin D genesSemantic proximity Read ↗

Structure of human cyclin-dependent kinase inhibitor p19INK4d: comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16INK4a.Semantic proximity Read ↗

The role of CDKN2A/B deletions in pediatric acute lymphoblastic leukemiaSemantic proximity Read ↗

NEDD4L on human chromosome 18q21 has multiple forms of transcripts and is a homologue of the mouse Nedd4-2 gene.Semantic proximity Read ↗

Expression of the cyclin-dependent kinase inhibitors p16INK4, p15INK4B and p21WAF1/CIP1 in human breast cancer.Semantic proximity Read ↗

Expression and localization of the CDC34 ubiquitin-conjugating enzyme in pediatric acute lymphoblastic leukemia.Semantic proximity Read ↗

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.