Article
[Molecular and functional diversity of inositol triphosphate-induced Ca(2+) release].
Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie - 1 Jan 1995
De Smedt H, Parys J B
Abstract excerpt
A remarkable duality concerning the role of intracellular Ca2+ ions is observed. At one side Ca2+ is a universal secondary messenger, and at the other side a prolonged increase of the Ca2+ concentration will lead to pathological conditions. This is the reason that Ca2+ signals occur in complex spatio-temporal patterns such as waves and oscillations. This behaviour reflects the existence of a fundamental...
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