Article
Influence of the major histocompatibility complex on age at onset of chronic lymphoid leukaemia.
International journal of cancer - 17 Jan 1996
Dorak M T, Machulla H K, Hentschel M, Mills K I, Langner J, Burnett A K
Abstract excerpt
The major histocompatibility complex is one of the interactive factors in the multifactorial model of carcinogenesis. Its main influence in experimental models is on the age at onset of malignancies. We have previously shown a similar effect of homozygosity for HLA-DR53 in CML. In the present stu...
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