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Article

HLA system affects the age-at-onset in chronic myeloid leukemia.

American journal of hematology - 1 Aug 2003

Oguz Fatma Savran, Kalayoglu Sevgi, Diler A Sarper, Tozkir Hilmi, Sargin Deniz, Carin Mahmut, Dorak M Tevfik

Abstract excerpt

Chronic myeloid leukemia (CML) occurs from childhood to old age. The adult form is characterized by the presence of Philadelphia chromosome resulting from bcr/abl translocation. The BCR-ABL fusion proteins are immunogenic, and the junctional sequences show unique HLA class I and class II restrict...

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Source

Identifiers

PMID: 12879429
DOI: 10.1002/ajh.10365

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12879429-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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