Article
EGF controls the in vivo developmental potential of a mammary epithelial cell line possessing progenitor properties.
The Journal of cell biology - 11 Nov 2002
Deugnier Marie-Ange, Faraldo Marisa M, Janji Bassam, Rousselle Patricia, Thiery Jean Paul, Glukhova Marina A
Abstract excerpt
The bilayered mammary epithelium comprises a luminal layer of secretory cells and a basal layer of myoepithelial cells. Numerous data suggest the existence of self-renewing, pluripotent mammary stem cells; however, their molecular characteristics and differentiation pathways are largely unknown. BC44 mammary epithelial cells in culture, display phenotypic characteristics of basal epithelium, i.e., express basal...
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