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Article

Amplification of lambda plasmids in Escherichia coli relA mutants.

Journal of biotechnology - 1 Dec 1995

Wegrzyn G

Abstract excerpt

It was previously demonstrated that, contrary to wild-type stringent (rel+) strains of Escherichia coli, in amino acid-starved relaxed (relA) mutants the replication of lambda plasmid proceeds for several hours. The replication leads to amplification of lambda plasmid DNA. Here, the conditions for this amplification have been optimized. The amplification efficiency depends on the temperature as well as on the...

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PMID: 8562019
DOI: 10.1016/0168-1656(95)00132-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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