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Article

Segregation analysis of continuous phenotypes by using higher sample moments.

American journal of human genetics - 1 Jan 1996

Lee H, Stram D O

Abstract excerpt

The present article discusses the use of computational methods based on generalized estimating equations (GEE), as a potential alternative to full maximum-likelihood methods, for performing segregation analysis of continuous phenotypes by using randomly selected family data. The method that we propose can estimate effect and degree of dominance of a major gene in the presence of additional nongenetic or...

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Identifiers

PMID: 8554059
PMCID: PMC1914965

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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