Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolutionary origins of retroposon lineages of Mhc class II Ab alleles.

Immunogenetics - 1 Jan 1996

Lu C C, Ye Y, She J X, Bonhomme F, Wakeland E K

Abstract excerpt

Major histocompatibility complex (Mhc) class II Ab genes have evolved into three distinct lineages. While lineage 2 alleles differ from lineage 1 alleles by the insertion of a retroposon in intron 2, the basis for the extremely large intron 2 in lineage 3 alleles has heretofore been undetermined. In this report, we demonstrate by nucleotide sequencing that the genomic sequences of prototypic alleles from all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to Evolution, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to Mice, Inbred Strains

Share to Molecular Sequence Data

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 8550095
DOI: 10.1007/BF00176672

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolutionary origins of retroposon lineages of Mhc class II Ab alleles.PMID 8550095Read ↗

Amplification of major histocompatibility complex class II gene diversity by intraexonic recombination.Semantic proximity Read ↗

Prevalence and evolutionary origins of autoimmune susceptibility alleles in natural mouse populations.Semantic proximity Read ↗

A highly polymorphic microsatellite in the class II Eb gene allows tracing of major histocompatibility complex evolution in mouse.Semantic proximity Read ↗

Evolution of a B2 tagged sequence from a long-range repeat family in the genus Mus.Semantic proximity Read ↗

RAG1/2 induces genomic insertions by mobilizing DNA into RAG1/2-independent breaksSemantic proximity Read ↗

Duplication and Variation in the Major Histocompatibility Complex Genes in Blakiston's Fish Owl, Bubo blakistoni.Semantic proximity Read ↗

Distinct evolution at TCRα and TCRβ loci in the genus <i>Mus</i>Semantic proximity Read ↗

454 sequencing reveals extreme complexity of the class II Major Histocompatibility Complex in the collared flycatcher.Semantic proximity Read ↗

Retroelements and segmental duplications in the generation of diversity within the MHC.Semantic proximity Read ↗

Two ancient allelic lineages at the single classical class I locus in the Xenopus MHC.Semantic proximity Read ↗

Mosaic genealogy of the Mus musculus genome revealed by 21 nuclear genes from its three subspecies.Semantic proximity Read ↗

Genetic variation and selection of MHC class I loci differ in two congeneric frogs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.