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Article

Angiotensin-converting enzyme genotype in children and coronary events in their grandparents.

Circulation - 15 Mar 1995

Badenhop R F, Wang X L, Wilcken D E

Abstract excerpt

BACKGROUND: It has been suggested that the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is an independent risk factor for coronary artery disease. The D/D genotype, which is associated with higher levels of circulating ACE than the I/D or I/I genotype, has been found significantly more frequently in patients with myocardial infarction and also in individuals with a...

Topics

Adolescent
Adult
Aged
Child
Child, Preschool
Coronary Disease
Female
Genotype
Humans
Lipoprotein(a)
Male
Middle Aged
Peptidyl-Dipeptidase A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Genetic

Risk Factors

Source

Identifiers

PMID: 7882471
DOI: 10.1161/01.cir.91.6.1655

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7882471-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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