Article
Angiotensin-converting enzyme genotype in children and coronary events in their grandparents.
Circulation - 15 Mar 1995
Badenhop R F, Wang X L, Wilcken D E
Abstract excerpt
BACKGROUND: It has been suggested that the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is an independent risk factor for coronary artery disease. The D/D genotype, which is associated with higher levels of circulating ACE than the I/D or I/I genotype, has been found significantly more frequently in patients with myocardial infarction and also in individuals with a...
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