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Article

Gene conversion in steroid 21-hydroxylase genes.

American journal of human genetics - 1 Jun 1990

Urabe K, Kimura A, Harada F, Iwanaga T, Sasazuki T

Abstract excerpt

The steroid 21-hydroxylase gene, CYP21B, encodes cytochrome P450c21, which mediates 21-hydroxylation. The gene is located about 30 kb downstream from pseudogene CYP21A. The CYP21A gene is homologous to the CYP21B gene but contains some mutations, including a C----T change which leads a termination codon, TAG, in the eighth exon. We found the same change in a mutant CYP21B gene isolated from a patient with...

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Identifiers

PMID: 1971153
PMCID: PMC1683832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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