Article
[Mechanisms of hereditary tumorigenesis].
Nihon rinsho. Japanese journal of clinical medicine - 1 Nov 1995
Takebe H
Abstract excerpt
Hereditary cancers have been shown to develop through at least two mechanisms. Development of retinoblastoma and Wilms' tumor is usually not accompanied by other hereditary symptoms. Although they are inherited autosomal dominantly, gene mutations in recessive tumor suppressor genes were found to...
Topics
- DNA Damage
- DNA Repair
- Genes, Tumor Suppressor
- Heterozygote
- Humans
- Mutation
- Neoplasms
