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Article

Characterization of the expressed CIITA allele in the class II MHC transcriptional mutant RJ2.2.5.

Immunogenetics - 1 Jan 1996

Brown J A, He X F, Westerheide S D, Boss J M

Abstract excerpt

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Topics

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Share to Gene Expression Regulation
Share to Genes, MHC Class II
Share to Nuclear Proteins
Share to Regulatory Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Sequence Deletion

Share to Trans-Activators

Share to Transcription, Genetic

Share to Transcriptional Activation

Source

Identifiers

PMID: 8537130
DOI: 10.1007/BF00186611

Genes

CIITA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of the expressed CIITA allele in the class II MHC transcriptional mutant RJ2.2.5.PMID 8537130Read ↗

The molecular basis of MHC class II deficiency and transcriptional control of MHC class II gene expression.Semantic proximity Read ↗

[MHC class II deficiency (CIITA/RFX deficiency)].Semantic proximity Read ↗

Three novel mutations of the CIITA gene in MHC class II-deficient patients with a severe immunodeficiency.Semantic proximity Read ↗

Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases.Semantic proximity Read ↗

Absence of MHC class II gene expression in a patient with a single amino acid substitution in the class II transactivator protein CIITA.Semantic proximity Read ↗

CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivation.Semantic proximity Read ↗

Two novel mutations in the MHC class II transactivator CIITA in a second patient from MHC class II deficiency complementation group A.Semantic proximity Read ↗

Three in vivo promoter phenotypes in MHC class II deficient combined immunodeficiency.Semantic proximity Read ↗

Defective MHC class II expression in an MHC class II deficiency patient is caused by a novel deletion of a splice donor site in the MHC class II transactivator gene.Semantic proximity Read ↗

Single nucleotide polymorphisms in MHC2TA, the gene encoding the MHC class II transactivator (CIITA).Semantic proximity Read ↗

Genetic complexity of regulatory mutants defective for HLA class II gene expression.Semantic proximity Read ↗

MHC class II-deficient tumor cell lines with a defective expression of the class II transactivator.Semantic proximity Read ↗

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