Article
Regulation of cell-matrix adhesion by receptor tyrosine kinases.
Leukemia & lymphoma - 1 Jul 1995
Kinashi T, Springer T A
Abstract excerpt
Cell-cell and cell-matrix adhesive interactions mediated by integrins play crucial roles in leukocyte migration to inflamed tissues, and also in cell migration during embryogenesis. Much remains to be learned about the molecular mechanisms of regulation of adhesion mediated by integrins. Recently we found that steel factor and c-kit induce adhesion to fibronectin by VLA-5 in mast cells. Activation of adhesiveness...
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