The molecular basis and specificity of integrin-ligand interactions

Abstract excerpt

Most eukaryotic cells have the ability to recognise and react functionally to adhesive extracellular matrices. This is true not only for actively migrating cells that use adhesive contact for traction and guidance, but also for stationary cells that require a platform for support and orientation. Cell-extracellular matrix adhesion has a homeostatic function in promoting tissue regeneration during wound healing,...

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