Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human smooth muscle VLA-1 integrin: purification, substrate specificity, localization in aorta, and expression during development.

The Journal of cell biology - 1 Nov 1990

Belkin V M, Belkin A M, Koteliansky V E

Abstract excerpt

A membrane glycoprotein complex was isolated and purified from human smooth muscle by detergent solubilization and affinity chromatography on collagen-Sepharose. The complex was identified as VLA-1 integrin and consisted of two subunits of 195 and 130 kD in SDS-PAGE. Liposomes containing the VLA-1 integrin adhered to surfaces coated with type I, II, III, and IV collagens, Clq subcomponent of the first component...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to SDS gene

Share to Ligands

Share to Microscopy, Fluorescence

Share to Organ Specificity

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 2229189
DOI: 10.1083/jcb.111.5.2159
PMCID: PMC2116325

Genes

SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human smooth muscle VLA-1 integrin: purification, substrate specificity, localization in aorta, and expression during development.PMID 2229189Read ↗

Integrin α2β1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cellsSemantic proximity Read ↗

Adhesion G protein-coupled receptor VLGR1/ADGRV1 regulates cell spreading and migration by mechanosensing at focal adhesionsSemantic proximity Read ↗

Laminin isoforms in endothelial and perivascular basement membranes.Semantic proximity Read ↗

Regulation of cell-matrix adhesion by receptor tyrosine kinases.Semantic proximity Read ↗

Perspectives series: cell adhesion in vascular biology. Integrin signaling in vascular biology.Semantic proximity Read ↗

Expression of collagen binding integrins during cardiac development and hypertrophy.Semantic proximity Read ↗

Alpha 8 integrin expression is required for maintenance of the smooth muscle cell differentiated phenotype.Semantic proximity Read ↗

Beta 1D integrin displaces the beta 1A isoform in striated muscles: localization at junctional structures and signaling potential in nonmuscle cells.Semantic proximity Read ↗

Expression and function of the integrin alpha9beta1 in bovine aortic valve interstitial cells.Semantic proximity Read ↗

Gene structure, chromosomal location, and basis for alternative mRNA splicing of the human VCAM1 gene.Semantic proximity Read ↗

Role for the α7β1 integrin in vascular development and integritySemantic proximity Read ↗

Expression of the α1β1 integrin, VLA-1, marks a distinct subset of human CD4+ memory T cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.