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Regulation and functions of integrin α2 in cell adhesion and disease

31 Dec 2018

Abstract excerpt

Integrins are cell adhesion molecules that are composed of an alpha (α) subunit and a beta (β) subunit with affinity for different extracellular membrane components. The integrin family includes 24 known members that actively regulate cellular growth, differentiation, and apoptosis. Each integrin heterodimer has a particular function in defined contexts as well as some partially overlapping features with other...

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PMID: 30906828
DOI: 10.1016/j.gendis.2018.12.003

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