Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma.

doi:10.1002/mpo.2950240402

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Article

Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma.

Medical and pediatric oncology - 1 Apr 1995

Caron H

Abstract excerpt

In neuroblastoma, N-myc amplification and loss of heterozygosity for the short arm of chromosome 1 (LOH 1p) are common genetic abnormalities. We have recently shown that the presence of additional material of the long arm of chromosome 17 (add.17q) also occurs relatively frequently. In the presen...

Topics

Alleles
Chromosome Deletion
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 17
DNA, Neoplasm
Genetic Markers
Heterozygote
Humans
Infant
Neuroblastoma
Prognosis
Survival Analysis

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